A patient who has been diagnosed with diabetes insipidus has been prescribed vasopressin as an antidiuretic replacement. The nurse caring for the patient reviews his other medications. Which drug should not be taken with vasopressin?

 

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Correct

- Carbamazepine (Tegretol)

- Levothyroxine (Synthroid)

- Diphenhydramine (Benadryl)

- Omeprazole (Prilosec)

Rationale

"Carbamazepine" is correct. Vasopressin is a medication that has the effects of anti-diuretic hormone. It can be used to control blood pressure and is used for treatment of diabetes insipidus. Vasopressin should not be used with carbamazepine, as carbamazepine can decrease the overall effects of vasopressin in the bloodstream.

"Levothyroxine", "Diphenhydramine" and "Omeprazole" are incorrect. These drugs do not have any known interactions with vasopressin.

References:
Drug Interaction Report. (n.d.). Retrieved from https://www.drugs.com/interactions-check.php?drug_list=497-0,2294-0

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