A 30-year-old female patient has been diagnosed with infertility as a result of polycystic ovary syndrome. The patient and her husband have been trying to become pregnant for over a year. The physician prescribes clomiphene citrate. Which of the following best describes how this drug can help to achieve pregnancy?

 

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Correct

- Clomiphene stimulates ovulation when a woman does not ovulate with PCOS

- Clomiphene increases the lining of the uterus to support the growth of a fertilized egg

- Clomiphene enhances the cervical environment to allow sperm to enter the uterus

- Clomiphene opens blocked fallopian tubes that may be closed by scarring

Rationale

"Clomiphene stimulates ovulation when a woman does not ovulate with PCOS" is correct. Clomiphene citrate (Clomid) is a drug used for the treatment of infertility. It stimulates ovulation in a woman's ovaries, which can increase the chance of becoming pregnant. Clomiphene also increases the chance of multiple eggs being released during ovulation, therefore increasing the chance of multiple births.

"Clomiphene increases the lining of the uterus to support the growth of a fertilized egg", "Clomiphene enhances the cervical environment to allow sperm to enter the uterus" and "Clomiphene opens blocked fallopian tubes that may be closed by scarring" are incorrect because Clomiphene works by stimulating ovulation.

References:
Clomiphene: MedlinePlus Drug Information. (2017, September 15). Retrieved from https://medlineplus.gov/druginfo/meds/a682704.html

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