Olanzapine (Zyprexa )

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What is the Generic Name for Zyprexa?

Olanzapine

What is the Trade Name for Olanzapine?

Zyprexa

What are the Indications of Olanzapine (Zyprexa )?

  • Schizophrenia, mania
  • Depression
  • Anorexia nervosa
  • Nausea/vomiting related to chemotherapy

What are the Actions of Olanzapine (Zyprexa )?

Antagonizes dopamine and serotonin

What is the Therapeutic Class of Olanzapine (Zyprexa )?

Antipsychotic, mood stabilizers

What is the Pharmacologic Class of Olanzapine (Zyprexa )?

Thienobenzodiazepines

What are the Nursing Considerations of Olanzapine (Zyprexa )?

  • Do not use while breastfeeding
  • Can cause neurolyptic malignant syndrome, seizures, suicidal thoughts, insomnia, tardive dyskinesia, agranulocytosis, constipation, tremors
  • Assess mental status
  • Monitor hemodynamics
  • Assess blood sugars
  • Assess intake and output
  • Monitor liver function tests

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