Meperidine (Demerol) Nursing Pharmacology Considerations

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What is the Generic Name for Demerol?

meperidine

What is the Trade Name for meperidine?

Demerol

What are the Indications of Meperidine (Demerol) Nursing Pharmacology Considerations?

moderate to severe pain, sedation

What are the Actions of Meperidine (Demerol) Nursing Pharmacology Considerations?

Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS.

What is the Therapeutic Class of Meperidine (Demerol) Nursing Pharmacology Considerations?

Opioid Analgesic

What is the Pharmacologic Class of Meperidine (Demerol) Nursing Pharmacology Considerations?

opioid agonists

What are the Nursing Considerations of Meperidine (Demerol) Nursing Pharmacology Considerations?

  • may cause alterations in mentation, hypotension, constipation, nausea, vomiting
  • assess BP, pulse, and respiratory rate prior to administration and frequently during administration
  • use caution if patient is receiving MAOIs
  • Narcan (naloxone) is the antidote for opioid agonists
  • can cause seizure
  • may increase pancreatic enzyme levels
  • assess bowel function

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