D-Dimer (DDI)

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What is the Lab Name for D-Dimer?

D-Dimer

What is the Lab Abbreviation for D-Dimer?

DDI

What is D-Dimer in terms of Nursing Labs?

D-dimer (DDI) is a product of fibrinolysis, the process of plasminogen breaking down fibrin clots. Two products are made by fibrinolysis: D-dimer (DDI) and Fibrin Degradation Products (FDP). D-dimer levels are elevated in the setting of clot breakdown, but will be even higher in the setting of Disseminated Intravascular Coagulation (DIC).

What is the Normal Range for D-Dimer?

≤ 250 ng/mL

What are the Indications for D-Dimer?

  • Identify and monitor Disseminated Intravascular Coagulation (DIC)
  • Rule out a blood clot:
    • Pulmonary Embolism (PE)
    • Deep Vein Thrombosis (DVT)
    • Stroke

What would cause Increased Levels of D-Dimer?

  • Surgery
  • Trauma
  • Infection
  • Cancer
  • Heart attack
  • Pregnancy
  • Deep Vein Thrombosis (DVT)
  • Disseminated Intravascular Coagulation (DIC)

What would cause Decreased Levels of D-Dimer?

  • N/A

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