What is Creatinine Clearance () in terms of Nursing Labs?
Creatinine is a byproduct of Creatine metabolism, and it is excreted in the kidneys. Creatinine is created in proportion to muscle mass and usually stays stable. Urine and blood levels are compared to determine creatinine clearance from the blood. Any disease that affects the kidneys ability to clear waste products will increase blood creatinine levels and decrease creatinine clearance levels.
What are the Indications for Creatinine Clearance?
- Used to determine:
- Kidney damage in renal disease
- Glomerular function
- Effectiveness of treatment
What would cause increased levels of Creatinine Clearance?
- Diabetes Mellitus (DM)
- High protein diets
What would cause decreased levels of Creatinine Clearance?
- Renal disease
- Congestive Heart Failure (CHF)
- Obstruction within kidney
Date Published - May 12, 2016
Date Modified - Jun 27, 2016