What Are You Struggling With?

Codeine (Paveral): allergy, cold, cough remedy, antitussive, opioid analgesic


Trade Name



management of pain, diarrhea, cough suppressant


Binds to opiate receptors in the CNS and alters perception of pain while producing a general depression of the CNS.  This depression also causes a decrease in the cough reflex and GI motility.

Therapeutic Class

allergy, cold, cough remedy, antitussive, opioid analgesic

Pharmacologic Class

opioid agonist

Nursing Considerations

  • may cause alterations in mentation, hypotension, constipation, nausea, vomiting
  • assess BP, pulse, and respiratory rate prior to administration and frequently during administration
  • use caution if patient is receiving MAO Inhibitors
  • Narcan (naloxone) is the antidote for opioid agonists


Date Published - Feb 26, 2016
Date Modified - May 23, 2019

Jon Haws RN

Written by Jon Haws RN

Jon Haws RN began his nursing career at a Level I Trauma ICU in DFW working as a code team nurse, charge nurse, and preceptor. Frustrated with the nursing education process, Jon started NRSNG in 2014 with a desire to provide tools and confidence to nursing students around the globe. When he's not busting out content for NRSNG, Jon enjoys spending time with his two kids and wife.