Aspart, Lispro, Glulisine Insulin (rapid acting): Novolog, Humalog, Apidra (antidiabetics, hormones)

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Generic Name

aspart, lispro, glulisine

 

Trade Name

novolog, humalog, apidra

Indication

hyperglycemia with diabetes type 1 and 2, diabetic ketoacidosis

Action

stimulates uptake of glucose into muscle and fat cells, inhibits production of glucose in the liver, prevents breakdown of fat and protein

RouteOnsetPeakDuration
Aspart10-20 min1-3 hr3-5 hr
Glulisine15 min1 hr2-4 hr
Lispro15 min1-1.5 hr3-4 hr

Therapeutic Class

antidiabetics, hormones

Pharmacologic Class

pancreatics

Nursing Considerations

  • assess for symptoms of hypoglycemia or hyperglycemia
  • monitor body weight over time
  • may cause decreased inorganic phosphates, potassium, and magnesium
  • monitor blood sugars every 6 hours, monitor A1C every 3-6 months

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