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Alkaline Phosphatase

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Alkaline Phosphatase

Lab Name:

Alkaline Phosphatase

What is Alkaline Phosphatase () in terms of Nursing Labs?

Alkaline phosphatase (ALP) is located in several places in the body: liver, intestines, biliary tract, bones, placenta.  Different isoenzymes of ALP can be used to determine different disorders: liver, bone, intestine, certain cancers.  It can also be used to determine bone turnover  in postmenopausal women.

What is the Normal Range for Alkaline Phosphatase?

40-130 U/L

What are the Indications for Alkaline Phosphatase?

  • Identifying
    • Hepatobiliary disease
    • Malignancies
    • Bone disease
    • Bone damage in renal patients
  • useful in evaluating bone growth in children.

What would cause increased levels of Alkaline Phosphatase?

  • Liver disease
  • Bone disease
  • Pregnancy
  • Amyloidosis
  • Lung cancer
  • Pancreatic cancer
  • Congestive heart failure
  • Ulcerative colitis
  • Hodgkin’s disease
  • Chronic renal failure
  • Sarcoidosis

What would cause decreased levels of Alkaline Phosphatase?

  • Hypophophatasia
  • Anemia
  • Kwashiorkor
  • Cretinism
  • Hypothyroidism
  • Zinc or magnesium deficiency
  • Scurvy

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Date Published - Apr 17, 2016
Date Modified - Jun 23, 2016